Disufenton sodium
Disufenton sodium is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
10 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Stroke | D020521 | EFO_0000712 | I63.9 | — | — | 2 | — | — | 2 |
| Ischemia | D007511 | EFO_0000556 | — | — | — | 2 | — | — | 2 |
| Transient ischemic attack | D002546 | EFO_0003764 | G45.9 | — | — | 2 | — | — | 2 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Glioma | D005910 | EFO_0000520 | — | 3 | 2 | — | — | 1 | 5 |
| Glioblastoma | D005909 | EFO_0000515 | — | 3 | 2 | — | — | — | 4 |
| Recurrence | D012008 | — | — | 1 | 1 | — | — | — | 2 |
| Astrocytoma | D001254 | EFO_0000271 | — | 2 | 1 | — | — | — | 2 |
| Oligodendroglioma | D009837 | EFO_0000631 | — | 2 | 1 | — | — | — | 2 |
| Hemorrhage | D006470 | MP_0001914 | R58 | — | 1 | — | — | — | 1 |
| Cerebral hemorrhage | D002543 | — | — | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hearing loss | D034381 | EFO_0004238 | H91.9 | 1 | — | — | — | — | 1 |
| Noise-induced hearing loss | D006317 | EFO_1001254 | — | 1 | — | — | — | — | 1 |
| Sensorineural hearing loss | D006319 | — | H90.5 | 1 | — | — | — | — | 1 |
| Deafness | D003638 | EFO_0001063 | H91.9 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Diffuse intrinsic pontine glioma | D000080443 | — | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Disufenton sodium |
| INN | disufenton sodium |
| Description | Disufenton sodium (Cerovive, OKN-007, NXY-059, HPN-07) is a free radical trapping nitrone-based antioxidant compound that has been under development for several medical conditions.
|
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(C)(C)[N+]([O-])=Cc1ccc(S(=O)(=O)[O-])cc1S(=O)(=O)[O-].[Na+].[Na+] |
Identifiers
| PDB | — |
| CAS-ID | 168021-77-0 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2107334 |
| ChEBI ID | — |
| PubChem CID | 6440181 |
| DrugBank | — |
| UNII ID | 7M1J3HN9VO (ChemIDplus, GSRS) |
Target
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Trends
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Safety
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Adverse Events
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